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. 2020 Sep 24;2020(9):CD013019. doi: 10.1002/14651858.CD013019.pub2

Oostra 2015.

Study characteristics
Methods RCT
Participants All patients sustained stroke between August 2009 and June 2013. Patients were recruited via the University Hospital and from hospitals in East and West Flanders to the Rehabilitation Centre, University Hospital of Ghent
MI training: 21, muscle relaxation: 23
Sample size: 44
Inclusion criteria: 1) had experienced a first‐ever stroke less than 1 year before entering the study; 2) able to walk 10 meters with minimal assistance (Functional Ambulation Category ≥ 3); 3) able to pass the Time Dependent Motor Imagery screening test; 4) between 16 and 70 years old; and 5) did not have psychiatric symptoms or any other neurological disease
Exclusion criteria: not reported by study authors
Mean (SD) age: MI training group: 50.3 (SD 12.8) years; muscle relaxation group: 53.7 (SD 12.0) years
Stroke details: MI training group: 13 ischaemic/8 hemorrhagic; muscle relaxation group: 15 ischemic/8 hemorrhagic
Stroke phase: subacute
Interventions Experimental group: MI training: practice was performed from an internal perspective with both a visual (“viewing” themselves performing the task) and kinesthetic mode (“feeling” the experience of performing the task), with emphasis on the latter
Control group: muscle relaxation: this group, on the other hand, received the same amount of muscle relaxation therapy over and above the standard rehabilitation training
All patients in both groups received a standard rehabilitation program, consisting of 2 hours physical therapy and 1 hour occupational therapy daily, 5 days per week
Outcomes Outcomes recorded at baseline and after 6 weeks of intervention
Walking speed: 10 Meter Walk Test.
Motor function: Lower‐extremity Fugl‐Meyer Assessment Scale
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: “a process of blinded random number allocation”
Allocation concealment (selection bias) High risk Not reported
Blinding of participants and personnel (performance bias)
All outcomes High risk All the participants had to be aware of the therapies to participate in the study, since it involved physical and cognitive exercise
Blinding of outcome assessment (detection bias)
All outcomes Low risk Quote: “the physician responsible for assessment of patients throughout the study remained blinded to the patients’ group allocation for the full duration of the trial"
Incomplete outcome data (attrition bias)
All outcomes Low risk Quote: “None of the participants dropped out during the study"
Selective reporting (reporting bias) Low risk Quote: “The 10‐m walk scores and lower extremity Fugl‐Meyer assessment (LE‐FMA) scores improved significantly in both groups after treatment (P < 0.001 for both values). We also found a significant group interaction effect for the 10‐m walk test (F(1,43) = 4.5, P < 0.05), revealing a significantly reduced walking duration in the MIT group compared with the MR group. There was no significant interaction between session and group for the LE‐FMA score".
Other bias Low risk None detected