Table 2.
The expression of AZIN2 in neurodegenerative diseases. The table sums up the basic information of the samples studied. The expression, investigated in human brain samples by immunohistochemistry, was strongest and most widely distributed in the cases of Alzheimer's disease (+++), followed by normal brain samples. In CADASIL and Lewy body dementias, only minor amounts (+, +/−) of AZI2 were detected.
| Diagnosis | Level of AZI2 expression | Number of cases (n) | Age, mean; range (years) | Gender (male : female) | Dementia |
|---|---|---|---|---|---|
| Lewy body dementia | +/− | 4 | 75; 63–81 | 2:2 | 4/4 |
| CADASIL‐dementia | + | 4 | 62; 58–64 | 3:1 | 4/4 |
| Alzheimer's disease | +++ | 15 | 81; 63–98 | 6:9 | 15/15 |
| Normal | +/++ | 17 | 41; 1–95 | 13:4 | 2/17 |