Ciray 2005.

Study characteristics
Methods	Single centre Power calculation not reported ITT analysis not stated Published as full paper
Participants	114 women from Turkey undergoing ART for ASRM grade 3 to 4 endometriosis only (poor prognosis) Age < 40 years; AH group 33.1 (4.2); control group 34.0 (3.7) Basal FSH: AH group 7.4 (3.5); control group 9.0 (5.1)
Interventions	Laser hatching (thinning to a quarter), 76 women randomised, 146 embryos transferred (16 cancelled) vs No hatching, only fresh embryo transfer cycles, 38 women randomised, 72 embryos transferred (8 cancelled)
Outcomes	Clinical pregnancy rate, implantation rate
Notes	No. of embryos: AH 2.4; control 2.4
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomised method stated 2:1 date, with the aid of computer programme
Allocation concealment (selection bias)	Unclear risk	Unclear; no details
Blinding (performance bias and detection bias) All outcomes	High risk	No evidence of blinding of participants or assessors
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women appear to have been analysed
Selective reporting (reporting bias)	Unclear risk	All outcomes reported but original protocol not viewed; live birth not reported
Other bias	Low risk	None identified