Petersen 2005.

Study characteristics
Methods	Randomised trial
Participants	150 women from Brazil undergoing ART cycles All participants had 1 failed treatment cycle Mean age: 34 years
Interventions	ICSI cycles only AH quarter‐laser thinning vs control AH: 35 women with 1 previous implantation failure, 40 women with repeated implantation failures Control: 35 women with 1 previous implantation failure, 40 women with repeated implantation failures
Outcomes	Live birth, clinical pregnancy, miscarriage, multiple pregnancy
Notes	Study author response No. of ET: mean 2.7
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random numbers table
Allocation concealment (selection bias)	Unclear risk	Unclear ‐ code ID to mask identity of participants but not clear how or who generated this
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not stated
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women randomised appear to have been analysed
Selective reporting (reporting bias)	Low risk	Original protocol not viewed but study authors did report on live birth
Other bias	Low risk	None identified