Ryan 1997.

Study characteristics
Methods	Single‐centre randomised trial
Participants	200 women from Sydney, Australia, undergoing ART cycles
Interventions	AH: Tyrode's complete breach ‐ hole chemical means on both fresh and frozen‐thawed embryos: 100 women Control: 100 women
Outcomes	Clinical pregnancy
Notes	Additional information received from first author regarding definition of pregnancy. No further publication planned Mean: ET 2.17
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random numbers table
Allocation concealment (selection bias)	Unclear risk	Unclear whether allocation concealed
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Unclear whether blinding took place
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women randomised appear to have been analysed
Selective reporting (reporting bias)	Unclear risk	Original protocol not viewed. Study authors did not report on live birth
Other bias	Unclear risk	Conference abstract