Stein 1995.
Study characteristics | ||
Methods | Single‐centre randomised trial | |
Participants | 154 women from Israel with repeated implantation failure (> 3 attempts) undergoing IVF Mean age not stated | |
Interventions | AH (mechanical; complete zona breach; ? hour egg retrieval to AH; 1.5 hour AH to transfer) vs no AH AH: 72 women randomised, 230 embryos transferred Control: 82 women randomised, 295 embryos transferred | |
Outcomes | Clinical pregnancy, miscarriage | |
Notes | Attempted to contact author about this study; no reply received Unclear whether power calculation performed ITT analysis unclear Published as full paper |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomisation stated but method unclear or incorrect |
Allocation concealment (selection bias) | Unclear risk | Unclear; no details |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Participants not blinded or unclear Assessor not blinded or unclear |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | ITT analysis unclear |
Selective reporting (reporting bias) | High risk | Original protocol not viewed but study authors did not report on live birth |
Other bias | Low risk | None identified |