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. 2009 Feb 27;20(1):222–233. doi: 10.1111/j.1750-3639.2009.00266.x

Figure 1.

Figure 1

2‐D gels immunoblotted with HNE antibody of entorhinal cortex from AD cases stages I/II (cases 2 and 6, upper panel) and controls (Ctrl 1 and 2, lower panel). Spots positive for HNE antibodies detected in AD but not in control cases are encircled. Note that several other spots appeared in case 2 but not in case 6. Similarly, additional spots appeared in Ctrl 2 but not in Ctrl 1. That means that other proteins in control and diseased brains are subject of oxidation. Only the spots appearing in all AD stage I/II cases and in none control were analyzed in detail. Abbreviations: 2‐D = two‐dimensional; AD = Alzheimer's disease.