Table 2.

Main clinical characteristics of the 11 GBM patients and summary of the spheres obtained from the A2B5⁺ fractions isolated from these samples. Abbreviations: EGFR: epidermal growth factor receptor; NA: not analyzed; SS: secondary spheres; SVZ: subventricular zone; TP: temporo parietal; F: frontal; S: sphenoidal.

Number	Date of birth	Topography	Contact with SVZ	Date of surgery	Date and state at the last follow up	Time (days) between cell culture and primary sphere formation	Maximum passages of SS	Genetic alterations
1	08/06/1926	Right frontal	–	06/02/2006	16/10/2007 (dead)	3	2	monosomy 10, EGFR amplification
2	17/08/1947	Left parieto‐occipital	–	27/03/2006	2/06/2008 (dead)	7	2	monosomy 10, EGFR amplification
3	20/04/1943	Right occipital inferior	+ TP	11/04/2006	21/11/2006 (dead)	12	3	monosomy 10
4	19/05/1959	Right frontal	–	17/05/2006	29/04/2008 (alive)	3	8	monosomy 10, EGFR amplification
5	12/12/1945	Left temporal	+ TP	19/06/2006	14/03/2007 (dead)	7	7	monosomy 10, EGFR amplification
6	04/11/1949	Fronto rolandic	+ F	03/07/2006	10/02/2007 (dead)	2	36	monosomy 10, EGFR amplification
7	22/02/1953	Right temporal	+ S	13/09/2006	29/05/2007 (dead)	10	18	monosomy 10
8	01/01/1935	Left frontal	–	29/12/2006	26/04/2007 (dead)	4	2	monosomy 10, EGFR amplification
9	15/09/1947	Left frontal	–	22/01/2007	3/07/2008 (dead)	6	34	monosomy 10, EGFR amplification
10	15/05/1938	Left temporal	–	07/02/2007	22/05/2007 (dead)	9	10	monosomy 10, EGFR amplification
11	03/03/1933	Right temporal	+ S	09/08/2007	06/06/2008 (alive)	10	7	monosomy 10, trisomy 7