Comparison 1. Systemic antibiotics versus no treatment/placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Resolution of ear discharge at 1 to 2 weeks	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1.1 Any antibiotic (mezlocillin or ceftazidime)	1	33	Risk Ratio (M‐H, Fixed, 95% CI)	8.47 [1.88, 38.21]
1.1.2 Mezlocillin	1	22	Risk Ratio (M‐H, Fixed, 95% CI)	8.27 [1.83, 37.47]
1.1.3 Ceftazidime	1	23	Risk Ratio (M‐H, Fixed, 95% CI)	8.31 [1.84, 37.59]