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. 2021 Feb 4;2021(2):CD013052. doi: 10.1002/14651858.CD013052.pub2

Comparison 5. Quinolones versus beta‐lactams.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Resolution of ear discharge (1 to 2 weeks) 3 702 Risk Ratio (M‐H, Fixed, 95% CI) 1.14 [0.97, 1.35]
5.1.1 Levofloxacin versus co‐amoxiclav 1 22 Risk Ratio (M‐H, Fixed, 95% CI) 1.25 [0.68, 2.28]
5.1.2 Pipemidic acid versus aminobenzylpenicillin 1 428 Risk Ratio (M‐H, Fixed, 95% CI) 1.15 [0.93, 1.42]
5.1.3 Norfloxacin versus aminobenzylpenicillin 1 252 Risk Ratio (M‐H, Fixed, 95% CI) 1.12 [0.85, 1.48]
5.2 Suspected ototoxicity 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
5.2.1 Dizziness or vertigo 1 22 Risk Ratio (M‐H, Fixed, 95% CI) 0.28 [0.01, 6.25]
5.2.2 Tinnitus 1 22 Risk Ratio (M‐H, Fixed, 95% CI) Not estimable