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. 2021 Feb 4;2021(2):CD013052. doi: 10.1002/14651858.CD013052.pub2

Comparison 7. Lincosamides versus nitroimidazoles (both study arms also received gentamicin).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
7.1 Resolution of ear discharge (1 to 2 weeks) 1 119 Risk Ratio (M‐H, Fixed, 95% CI) 0.74 [0.55, 1.00]
7.1.1 Lincomycin versus metronidazole 1 55 Risk Ratio (M‐H, Fixed, 95% CI) 0.73 [0.47, 1.14]
7.1.2 Clindamycin versus metronidazole 1 64 Risk Ratio (M‐H, Fixed, 95% CI) 0.75 [0.50, 1.12]
7.2 Resolution of ear discharge (2 to 4 weeks) 1 119 Risk Ratio (M‐H, Fixed, 95% CI) 0.72 [0.53, 0.98]
7.2.1 Lincomycin versus metronidazole 1 55 Risk Ratio (M‐H, Fixed, 95% CI) 0.69 [0.44, 1.09]
7.2.2 Clindamycin versus metronidazole 1 64 Risk Ratio (M‐H, Fixed, 95% CI) 0.75 [0.50, 1.12]
7.3 Resolution of ear discharge (after 4 weeks) 1 119 Risk Ratio (M‐H, Fixed, 95% CI) 0.68 [0.48, 0.96]
7.3.1 Lincomycin versus metronidazole 1 55 Risk Ratio (M‐H, Fixed, 95% CI) 0.66 [0.39, 1.11]
7.3.2 Clindamycin versus metronidazole 1 64 Risk Ratio (M‐H, Fixed, 95% CI) 0.70 [0.44, 1.10]