8. Comparison 5. Desipramine versus placebo: substance misuse.
Study | Outcomea |
Experimental group (n = 17 completed) |
Control group (n = 12 completed) |
Statisticc |
Arndt 1994 | ASI (drug factor scores)b | 0.259 | 0.23 | Favours neither condition (P > 0.05) |
Arndt 1994 | Days of opiate use | 2 | 2 | Favours neither condition (P > 0.05) |
Arndt 1994 | Days of cocaine use | 9 | 8 | Favours neither condition (P > 0.05) |
Arndt 1994 | Cocaine craving scores | 8 | 7 | Favours neither condition (P > 0.05) |
ANCOVA: Analysis of covariance; ASI: Addiction Severity Index |
a12‐week end of treatment means bASI factor scores range from 0 to 1 with larger values indicating greater problem severity cBetween‐groups ANCOVA using baseline value as covariate; baseline values reflect the 30 days before start of treatment; analysis carried out by trial investigators