Comparison 3. Neuropsychiatric status.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
3.1 Neuropsychiatric status (change from baseline, short term)	2	136	Std. Mean Difference (IV, Random, 95% CI)	‐0.48 [‐0.82, ‐0.13]
3.2 Neuropsychiatric status (change from baseline, medium term)	3	410	Std. Mean Difference (IV, Fixed, 95% CI)	‐0.27 [‐0.47, ‐0.08]
3.3 Neuropsychiatric status (change in NPI from baseline, long term)	1	108	Mean Difference (IV, Fixed, 95% CI)	‐0.87 [‐8.42, 6.68]