| Date | Event | Description |
|---|---|---|
| 21 November 2014 | Amended | Added new data for progression‐free survival analysis for Schema 1 (where drugs changed on disease progression). The analysis now includes a comparison of time to first progression in the combination arm versus time to first progression (not after second progression) in the sequential arm (refer to analyses 2.1, 9.1, 16.1, 23.1 and 30.1). This review version also includes new data obtained for Sledge 2003. |
| 21 January 2014 | Amended | Corrected labels for Analysis 10.1, 17.1, 24.1 (Figure 6) and 31.1, and also the number of participants in the Beslija trial for the outcome overall response |