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. 2020 Sep 29;2020(9):CD007239. doi: 10.1002/14651858.CD007239.pub4

Summary of findings 6. Specialist breastfeeding education compared to usual care for preventing mastitis after childbirth.

Specialist breastfeeding education compared to usual care for preventing mastitis after childbirth
Patient or population: postpartum breastfeeding women
Setting: obstetric outpatient clinic
Intervention: specialist breastfeeding education
Comparison: usual care
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with usual care Risk with specialist breastfeeding education
Incidence of mastitis within 6 months postpartum Study population RR 0.93
(0.17 to 4.95) 203
(1 RCT) ⊕⊕⊝⊝
LOW 1 This outcome was measured at 30 days postpartum
30 per 1000 28 per 1000
(5 to 150)
Recurrence of mastitis within 12 months postpartum Not reported
Breast abscess within 6 months postpartum Not reported
Nipple damage within 6 months postpartum Not reported
Duration of any breastfeeding Not reported
Breast pain (sore nipples) Study population RR 0.93
(0.36 to 2.37) 203
(1 RCT) ⊕⊕⊝⊝
LOW 1  
91 per 1000 85 per 1000
(33 to 215)
Number of women with adverse events Not reported
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio; OR: Odds ratio;
GRADE Working Group grades of evidenceHigh certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Downgraded two levels due to imprecision: single small trial with wide 95% CIs, indicating that the true effect may be either appreciable benefit or harm