Bora 2017.
| Study characteristics | ||
| Methods | Randomised controlled trial | |
| Participants | 107 "stable" VLBW infants (1000–1500 g birth weight), irrespective of gestational age at birth Setting: Department of Paediatrics, Assam Medical College, Assam, India |
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| Interventions | Intervention (n = 52): full enteral feeds (80 mL/kg/day) with expressed breast milk or donor breast milk Control (n = 55): minimal enteral feeds (20 mL/kg/day) supplemented with intravenous 10% dextrose Feed volumes increased by 20 mL/kg/day as tolerated |
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| Outcomes |
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| Notes | Human milk was enriched with a multi‐nutrient fortifier when infants reached an intake volume of volume of 100 mL/kg/day. The intervention group contained more infants born to mothers with pregnancy induced hypertension (51%) than the control group (31%). |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Computer‐generated. |
| Allocation concealment (selection bias) | Low risk | Sealed opaque envelopes. |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | Not masked. |
| Blinding of outcome assessment (detection bias) All outcomes | High risk | Not masked. |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Near‐complete (103/107 participants). |
| Selective reporting (reporting bias) | Unclear risk | No protocol to compare. All outcomes in methods section reported. |
| Other bias | Unclear risk | No funding source reported. |