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. 2021 Mar 21;2021(3):CD012799. doi: 10.1002/14651858.CD012799.pub2

Comparison 5. Subgroup analysis: different doses of fluoxetine.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Study withdrawal due to adverse events 3 72 Risk Ratio (M‐H, Random, 95% CI) 2.09 [0.26, 16.82]
5.1.1 Fluoxetine 20 mg daily 3 72 Risk Ratio (M‐H, Random, 95% CI) 2.09 [0.26, 16.82]
5.2 Adverse events 4 140 Risk Ratio (M‐H, Random, 95% CI) 2.50 [1.29, 4.86]
5.2.1 Fluoxetine 20 mg daily 2 57 Risk Ratio (M‐H, Random, 95% CI) 9.32 [1.88, 46.26]
5.2.2 Fluoxetine 40 mg daily 1 23 Risk Ratio (M‐H, Random, 95% CI) 2.29 [0.55, 9.49]
5.2.3 Fluoxetine 90 mg daily 1 60 Risk Ratio (M‐H, Random, 95% CI) 1.78 [0.76, 4.17]
5.3 Intravaginal ejaculatory latency time 5 149 Mean Difference (IV, Random, 95% CI) 2.46 [1.52, 3.39]
5.3.1 Fluoxetine 20 mg daily 3 66 Mean Difference (IV, Random, 95% CI) 2.87 [1.26, 4.48]
5.3.2 Fluoxetine 40 mg daily 1 23 Mean Difference (IV, Random, 95% CI) ‐0.54 [‐3.57, 2.49]
5.3.3 Fluoxetine 90 mg daily 1 60 Mean Difference (IV, Random, 95% CI) 2.72 [1.83, 3.61]
5.4 Depression 1 14 Risk Ratio (M‐H, Random, 95% CI) 2.00 [0.23, 17.34]
5.4.1 Fluoxetine 20 mg daily 1 14 Risk Ratio (M‐H, Random, 95% CI) 2.00 [0.23, 17.34]