Ahn 1996.

Study characteristics
Methods	Study design: randomized controlled, parallel‐group trial Setting/country: Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea Dates study conducted: NR
Participants	Inclusion criteria: Heterosexual sexually active men with PE Age 18–75 years PE defined as IELT ≤ 2 minutes after vaginal intromission in half of the intercourse Exclusion criteria: ED Alcohol and drug abuse Physical illness Use of psychoactive drugs Number of participants randomized: 23 Group 1 (fluoxetine) Number of participants randomized: 12 Age (mean): 39.8 (range 34–48) years Group 2 (placebo) Number of participants randomized: 11 Age (mean): 41.8 (range 31–61) years
Interventions	Group 1: fluoxetine 20 mg daily for first 1 week and 40 mg daily for remaining 5 weeks after breakfast Group 2: multivitamin as placebo daily
Outcomes	Primary outcomes: IELT How measured: NR Time points measured: 0, 3, 6 weeks Safety outcomes: Adverse effects How measured: reported Time points measured: anytime
Funding sources	NR
Declarations of interest	NR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: "participants and investigator were blinded for the randomization," "randomized placebo controlled trial."
Blinding of outcome assessment (detection bias) Participant‐reported outcomes	Low risk	Quote: "participants and investigator were blinded for the randomization," "randomized placebo controlled trial."
Blinding of outcome assessment (detection bias) Investigator‐assessed outcomes	Low risk	Quote: "investigator were blinded for the randomization."
Blinding of outcome assessment (detection bias) IELT	Low risk	Objective measurement that was unlikely to be influenced by blinding.
Incomplete outcome data (attrition bias) All outcomes	Low risk	All participants included in analysis.
Selective reporting (reporting bias)	Unclear risk	Unpublished protocol/prespecified outcomes (intercourse frequency, libido) in method were not or were partially reported in the results.
Other bias	Low risk	No additional sources of bias identified.