Skip to main content
. 2021 Feb 25;2021(2):CD010668. doi: 10.1002/14651858.CD010668.pub2

Tanaka 2017.

Methods Multicenter, placebo‐controlled RCT, 52 weeks
Participants Age 18 or over with qualifying SELENA‐SLEDAI score
Interventions IV belimumab 10 mg/kg or placebo every 28 days, plus standard SLE therapy
Outcomes Reduction in steroid dose, adverse events
Notes N = 677; belimumab effective in steroid reduction

IV: intravenous
RCT: randomized controlled trial
SELENA‐SLEDAI: Safety of Estrogen in Lupus National Assessment (SELENA) ‐ Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)
SLE: systemic lupus erythematosus
SLEDAI‐2K: Safety of Estrogen in Lupus National Assessment (SELENA) ‐ Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) 2000