Tanaka 2017.
Methods | Multicenter, placebo‐controlled RCT, 52 weeks |
Participants | Age 18 or over with qualifying SELENA‐SLEDAI score |
Interventions | IV belimumab 10 mg/kg or placebo every 28 days, plus standard SLE therapy |
Outcomes | Reduction in steroid dose, adverse events |
Notes | N = 677; belimumab effective in steroid reduction |
IV: intravenous RCT: randomized controlled trial SELENA‐SLEDAI: Safety of Estrogen in Lupus National Assessment (SELENA) ‐ Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) SLE: systemic lupus erythematosus SLEDAI‐2K: Safety of Estrogen in Lupus National Assessment (SELENA) ‐ Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) 2000