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. 2020 Dec 11;2020(12):CD013814. doi: 10.1002/14651858.CD013814

Comparison 1. Acupuncture vs sham intervention.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Pain intensity (VAS) 8   Mean Difference (IV, Random, 95% CI) Subtotals only
1.1.1 Immediately after 7 1403 Mean Difference (IV, Random, 95% CI) ‐9.22 [‐13.82, ‐4.61]
1.1.2 Short term 5 1095 Mean Difference (IV, Random, 95% CI) ‐10.04 [‐17.22, ‐2.85]
1.1.3 Intermediate term 4 1138 Mean Difference (IV, Random, 95% CI) ‐3.83 [‐6.57, ‐1.09]
1.2 Back‐specific function 5   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
1.2.1 Immediately after (RMDQ, ODI, HFAQ) 5 1481 Std. Mean Difference (IV, Random, 95% CI) ‐0.16 [‐0.38, 0.06]
1.2.2 Short term (ODI, HFAQ) 3 957 Std. Mean Difference (IV, Random, 95% CI) ‐0.38 [‐0.69, ‐0.07]
1.2.3 Intermediate term (RMDQ, ODI, HFAQ) 4 1373 Std. Mean Difference (IV, Random, 95% CI) ‐0.16 [‐0.27, ‐0.05]
1.3 Quality of life 2   Mean Difference (IV, Random, 95% CI) Subtotals only
1.3.1 Immediately after (SF‐36) 2 157 Mean Difference (IV, Random, 95% CI) 4.42 [‐1.34, 10.18]
1.4 Quality of life 3   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
1.4.1 Short term (SF‐36, SF‐12 physical) 3 1068 Std. Mean Difference (IV, Random, 95% CI) 0.24 [0.03, 0.45]
1.4.2 Intermediate term (SF‐36, SF‐12 physical) 3 1066 Std. Mean Difference (IV, Random, 95% CI) 0.21 [0.09, 0.33]
1.5 Pain‐related disability (PDI) 2   Mean Difference (IV, Random, 95% CI) Subtotals only
1.5.1 Immediately after 2 285 Mean Difference (IV, Random, 95% CI) ‐3.28 [‐6.39, ‐0.17]
1.5.2 Intermediate term 2 269 Mean Difference (IV, Random, 95% CI) ‐2.91 [‐6.33, 0.51]
1.6 Global assessment of therapy effectiveness (6‐point scale) 1   Mean Difference (IV, Random, 95% CI) Subtotals only
1.6.1 Immediately after 1 744 Mean Difference (IV, Random, 95% CI) ‐0.30 [‐0.49, ‐0.11]
1.6.2 Short term 1 747 Mean Difference (IV, Random, 95% CI) ‐0.30 [‐0.49, ‐0.11]
1.6.3 Intermediate term 1 751 Mean Difference (IV, Random, 95% CI) ‐0.20 [‐0.39, ‐0.01]
1.7 Global assessment of therapy effectiveness (effective number) 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.7.1 Immediately after 2 163 Risk Ratio (M‐H, Random, 95% CI) 1.23 [1.04, 1.46]
1.7.2 Short term 2 141 Risk Ratio (M‐H, Random, 95% CI) 1.88 [0.66, 5.36]
1.8 Adverse events 4 465 Risk Ratio (M‐H, Random, 95% CI) 0.68 [0.46, 1.01]