The content of vasoactive substances and clotting factors in serum of of activating transcription factor 4 (ATF4) knockout mice induced by high salt. (A–G) nitric oxide (NO), endothelin 1 (ET-1), endothelial protein C receptor (EPCR), thrombin (TM), von Willebrand factor (vWF), tissue plasminogen activator (tPA), and plasminogen activator inhibitor (PAI). WT-NS – wild-type+normal salt group; WT-HS – wild-type+high salt group; KO-NS – ATF4+/−+normal salt group; KO-HS – ATF4+/−+high salt group. * P<0.05.