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. 2021 Apr 6;11:657665. doi: 10.3389/fonc.2021.657665

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Copyright © 2021 Wang, Yang, Feng, Zhu, Qiu, Hu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The heat map of 32 top apigenin-modulated miRNAs in Huh 7 cells. (A) The hierarchical clustering analysis was performed to analyze the average TPM expression of miRNAs in Huh 7 cells treated with 10 µM apigenin vs. 0.1% DMSO. (B) The hierarchical clustering analysis was performed to analyze the P value and Log2Fold of the 32 top apigenin-modulated miRNAs (P value ≤ 0.001⁾. Red indicates high relative expression and pink indicates low relative expression.