Table 3.
Overall | Rheumatoid arthritis | Psoriatic arthritis | Ankylosing spondylitis | |||||
---|---|---|---|---|---|---|---|---|
N = 341 | N = 197 | N = 85 | N = 59 | |||||
Univariate (95% CI) | Multivariate* (95% CI) | Univariate (95% CI) | Multivariate* (95% CI) | Univariate (95% CI) | Multivariate* (95% CI) | Univariate (95% CI) | Multivariate* (95% CI) | |
GH, score 0–100, Δ T1-T0 | ||||||||
Age, 1-year unit | 0.04 (− 0.09, 0.17) | − | 0.13 (− 0.05, 0.31) | − | − 0.10 (− 0.36, 0.16) | − | 0.10 (− 0.23, 0.44) | − |
Male Female as ref |
− 1.37 (− 4.8, 2.1) | − | − 5.8 (− 11.70, 0.03) | − | 1.29 (− 4.56, 7.15) | − | 0.25 (− 7.70, 8.2) | − |
TNFi Other bDMARDs as ref |
3.05 (− 0.53, 6.61) | − | 3.08 (− 1.73, 7.90) | − | 3.81 (− 2.76, 10.37) | − | − 4.95 (− 18.57, 8.67) | − |
GH at baseline | − 0.15 (− 0.21, − 0.10) | − | − 0.18 (− 0.25, − 0.10) | − | − 0.10 (− 0.22, 0.02) | − | − 0.14 (− 0.26, − 0.02) | − |
At least 1 visit | − 1.61 (− 5.12, 1.89) | − 0.59 (− 3.97, 2.79) | − 3.70 (− 8.57, 1.17) | − 1.99 (− 6.60, 2.62) | 0.07 (− 6.08, 6.24) | 0.42 (− 5.88, 6.72) | 5.54 (− 3.08, 14.16) | 8.87 (0.57, 17.16) |
VAS pain, score 0–100, Δ T1–T0 | ||||||||
Age, 1-year unit | 0.10 (− 0.02, 0.23) | − | 0.20 (0.03, 0.37) | − | − 0.10 (− 0.36, 0.16) | − | 0.35 (− 0.0004, 0.70) | |
Male Female as ref |
− 1.03 (− 4.43, 2.37) | − | − 2.87 (− 8.50, 2.75) | − | − 0.98 (− 6.94, 4.98) | − | − 1.34 (− 9.94, 7.25) | |
TNFi Other bDMARDs as ref |
0.70 (− 2.83, 4.22) | − | 0.74 (− 3.87, 5.34) | − | 1.63 (− 5.09, 8.35) | − | − 10.48 (− 25.00, 4.04) | |
GH at baseline | − 0.17 (− 0.22, − 0.11) | − | − 0.18 (− 0.26, − 0.11) | − | − 0.12 (− 0.24, 0.01) | − | − 0.17 (− 0.30, − 0.05) | |
At least 1 visit | − 4.3 (− 7.70, − 0.85) | − 2.9 (− 6.21, 0.34) | − 3.99 (− 8.62, 0.64) | − 2.28 (− 6.61, 2.06) | − 5.87 (− 12.01, 0.27) | − 5.32 (− 11.60, 0.95) | − 1.80 (− 11.25, 7.64) | 5.54 (− 2.99, 14.07) |
CI confidence interval, GH general health, TNFi tumor necrosis factor inhibitor, VAS visual analog scale, T0 patient-reported outcome evaluation before lockdown (between 1st January 2020 and 1st March 2020), T1 patient-reported outcome evaluation after lockdown (between 1st June 2020 and 1st August 2020), Δ T1–T0 Variation between patient-reported outcomes in T1 and T0,
*Adjusted for age, gender, anti-tumor necrosis factor therapy, and baseline patient-reported outcomes