Table 3.
Salivary levels of CRP, IL-6, TNF-α and HbA1C in Type 2 Diabetics and healthy controls
| Salivary biomarkers | Mean | Standard deviation | Median | Interquartile range | Test Statistics | p-value |
|---|---|---|---|---|---|---|
| (Q3–Q1) | ||||||
| CRP (μg/ml) | ||||||
| Controls | 0.02 | 0.02 | 0.01 | (0.021–0.001) = 0.02 | ||
| Diabetics | 0.05 | 0.04 | 0.04 | (0.062–0.023) = 0.04 | − 4.938* | < 0.0001 |
| IL-6 (pg/ml) | ||||||
| Controls | 41.94 | 16.88 | 48 | (53.50–26.0) = 27.5 | − 1.2828** | 0.2036 |
| Diabetics | 47.2 | 18.49 | 50 | (60.0–28.0) = 32.0 | ||
| TNF α (pg/ml) | ||||||
| Controls | 1.51 | 3.66 | 0.13 | (0.215–0.108) = 0.11 | − 2.100* | 0.0357 |
| Diabetics | 5.39 | 12.1 | 0.2 | (3.661–0.122) = 3.54 | ||
| HbA1c (%) | ||||||
| Controls | 4.79 | 0.65 | 4.6 | (5.10–4.35) = 0.75 | − 6.327* | < 0.0001 |
| Diabetics | 7.34 | 2.02 | 6.9 | (9.40–5.60) = 3.80 |
*Mann–Whitney U test
**Paired t test