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CYB5R3 mutation status in the three cohorts studied. Results in number (%)
| Mutation status | Zambian children with malaria (N = 165) | PUSH: US SCD children/ adolescents (N = 267) | Walk-PHaSST: US/ UKSCD adolescents/ adults (N = 321) |
| CYB5R3 wildtype subjects | 75 (45.5%) | 136 (50.9%) | 148 (46.1%) |
| CYB5R3c350C > G heterozygotes | 78 (47.3%) | 109 (40.8%) | 135 (42.1%) |
| CYB5R3c350C > G homozygotes | 12 (7.3%) | 22 (8.2%) | 38 (11.8%) |
