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. 2007 Jul 4;17(4):347–353. doi: 10.1111/j.1750-3639.2007.00075.x

Figure 5.

Figure 5

Transport of fluorescein (FITC‐)‐conjugated Aβ1‐40 and Aβ1‐42 into membrane vesicles from LLC‐MDR1 and control cells. (A,C) Membrane vesicles were incubated with 5 µM FITC‐Aβ1‐40 (A) and Aβ1‐42 (C) in the presence of 4 mM ATP (▴) or 4 mM 5′‐AMP (▾). Vesicle‐associated fluorescence was determined by size‐exclusion centrifugation. (B,D) Net ATP‐dependent transport into the vesicles from LLC‐MDR1 (▪) and from LLC (□) cells was calculated by subtracting values obtained in the presence of 5′‐AMP from those obtained in the presence of ATP. Data represent means ± SD (n = 4).