Table 3.
Semiquantitative analysis of immunohistochemical data for cyclin‐dependent kinase 5 (Cdk5), p35 and p‐Cdk5 expression in human brain tissue. −, no staining; +, some staining; ++, strong staining; +++, very strong staining; EC = endothelial cell.
| Patient no. | Cdk5 | p35 | p‐Cdk5 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Neurons | Glia | EC | Neurons | Glia | EC | Neurons | Glia | EC | |
| Contralateral hemisphere | Weak 1/2 + (cytoplasmic) | − | 1/2 + | Weak 1/2 + (cytoplasmic) | − | − | Weak 1/2 + (cytoplasmic) | Weak 1/2 + | − |
| 2 (3‐day survival) | +++ (nuclear) | ++ | ++ | +++ (nuclear) | + | + | +++ (nuclear) | +++ | + |
| 4 (5‐day survival) | +++ (nuclear) | +++ | ++ | ++ (nuclear) | ++ | +++ | + | ++ | ++ |
| 5 (6‐day survival) | +++ (nuclear) | ++ | ++ | ++ (nuclear) | ++ | +++ | ++ (nuclear) | ++ | +++ |
| 6 (6‐day survival) | ++ | + | ++ | +++ | ++ | ++ | ++ | + | + |
| 9 (15‐day survival) | ++ | ++ | ++ | +++ | ++ | ++ | ++ | + | ++ |
| 12 (26‐day survival) | +++ (nuclear) | ++ | +++ | ++ | ++ | + | +++ | ++ | + |
| 14 (34‐day survival) | + | − | + | + | + | + | − | − | − |
| 15 (37‐day survival) | +++ (cytoplasmic) | + | ++ | + | + | + | + | + | +++ |