Growth Characteristics of IOMM‐Lee skull base xenografts. Tissue sections of IOMM‐Lee xenografts on day 6 (A), day 9 (B–D) and day 12 (E,F) were stained with human vimentin (A) or hematoxylin and eosin (B–F) and examined to evaluate the pattern of tumor growth. IOMM‐Lee tumor growth maintained a well‐demarcated boundary with the brain, except for microinvasion of the brain by small clumps of tumor cells (C). s, skull; b, brain.