Table 1.

Clinical and diagnostic characteristics of the six cases of neuro‐invasive WNV infection. Abbreviations: WNV = West Nile virus; WID = WNV illness duration; H&E = hematoxylin and eosin; IHC = immunohistochemistry; PCR = polymerase chain reaction; NR = not reported; M = male; F = female; ND = not done; CSF = cerebrospinal fluid.

Case	Citation	Age/sex (years)	Predisposing history	WID (days)	WNV serology positive samples	H&E inflammatory lesions positive organs	WNV IHC positive organs	WNV PCR positive organs
1*	37	87/M	None	11	CSF, Serum	Brain	Brain	Brain, CSF, spleen, kidney
2†	10, 53	43/M	Renal transplant, diabetes mellitus	14	Serum	Brain, kidney, testes, skeletal muscle	Brain, kidney, lung, pancreas, thyroid, small bowel, prostate, testes, skin, bile duct, stomach	Brain
3	NR	75/F	Diabetes mellitus, cerebrovascular disease, high blood pressure	8	CSF	Brain	Brain, kidney, esophagus	ND
4	NR	26/M	Small bowel transplant	142	CSF, Serum	Brain	Brain, kidney, lung, pancreas, thyroid, colon	ND
5	28	46/F	Non‐Hodgkin lymphoma, bone marrow transplant	17	CSF, Serum	Brain	Brain, kidney	Brain, blood
6	NR	66/M	None	18	CSF, Serum	Brain	Brain	ND

Summary of demographic and pathological findings in six cases of neuro‐invasive WNV presumed secondary to mosquito bite.

^* WNV culture was positive on the brain, CSF, spleen and kidney of Case 1.

^† WNV electron microscopy was positive in the testis of Case 2.