Table 1.
Histopathological classification of childhood medulloblastomas. GNB = ganglioneuroblastoma; LC/A = large cell/anaplastic; MBEN = medulloblastoma with extensive nodularity; N/D = nodular/desmoplastic. The gray hatching encompasses tumors with an anaplastic phenotype.
Main category | Sub‐category | Variant | Sub‐variant | ||||
---|---|---|---|---|---|---|---|
Non‐desmoplastic | 299 (95%) | Non‐nodular | 280 (89%) | Classic | 225 (71%) | ||
GNB | 3 (1%) | GNB classic | 2 (<1%) | ||||
GNB anaplastic | 1 (<1%) | ||||||
LC/A | 52 (17%) | Large cell | 5 (2%) | ||||
Anaplastic | 47 (15%) | ||||||
Nodular | 19 (6%) | Biphasic (nodular/non‐desmoplastic) | 19 (6%) | Biphasic anaplastic | 3 (1%) | ||
Biphasic classic | 16 (5%) | ||||||
Desmoplastic | 16 (5%) | Nodular | 16 (5%) | N/D | 14 (4%) | Typical N/D | 11 (3%) |
Paucinodular N/D | 3 (1%) | ||||||
MBEN | 2 (<1%) |