Table 5.
Multivariate analysis of clinicopathological variables among children in the CNS9102 cohort. EFS = event‐free survival; LC/A = large cell/anaplastic; N/D = nodular/desmoplastic; OS = overall survival.
| OS | EFS | ||||
|---|---|---|---|---|---|
| Hazard ratio | P‐value | Hazard ratio | P‐value | ||
| Metastatic disease at presentation | Yes | 2.59 | P < 0.001 | 2.15 | P < 0.001 |
| No | 1.00 | 1.00 | |||
| Pathological variant | LC/A | 5.21 | P = 0.024 | 5.80 | P = 0.016 |
| Classic | 3.02 | P = 0.123 | 3.28 | P = 0.098 | |
| N/D | 1.00 | 1.00 | |||
| Radiotherapy schedule | RT not given | 3.60 | P < 0.001 | 3.10 | P = 0.002 |
| >50 days | 1.29 | P = 0.255 | 1.29 | P = 0.253 | |
| <50 days | 1.00 | 1.00 | |||
| Extent of resection | Subtotal | 1.58 | P = 0.017 | ||
| Total | 1.00 | ||||