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. 2008 Apr 15;18(4):533–547. doi: 10.1111/j.1750-3639.2008.00156.x

Figure 4.

Figure 4

Weak endothelial nitric oxide synthase (eNOS) expression is detected in some blood vessels (arrows) in the hippocampus in a 1‐day‐old control rat (A). The eNOS expression is enhanced drastically in the blood vessels (arrows) at 3 h after the hypoxic exposure (B). Scale bars: A,B = 50 µm. C and D show the neuronal nitric oxide synthase (nNOS) expression in the hippocampus. Weak nNOS expression is detected in the CA1 region of the hippocampus in a 1‐day‐old control rat (C); the expression is enhanced at 24 h after the hypoxic exposure (D). Scale bars: C,D = 50 µm. E and F show the inducible nitric oxide synthase (iNOS) expression in the hippocampus. Weak iNOS expression is present in some neurons in CA3 but not in the dentate gyrus (E). At 24 h after the hypoxic exposure, many neurons in the CA3 and dentate gyrus are expressing intense iNOS immunoexpression (F). Scale bars: E,F = 100 µm. G and H show iNOS immunoexpression in granule cells (arrows, G) and CA3 neurons (arrows, H) at 24 h after the exposure. Scale bars: G,H = 10 µm.