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Aβ immunohistochemistry in unimmunized Alzheimer's disease (AD) and after Aβ42 immunization. Pattern of Aβ immunoreactivity (pan‐Aβ antibody, residues 8–17) in the parietal lobe of an unimmunized AD case (AD) and an immunized AD case (iAD). The AD case reveals the presence of numerous Aβ plaques in the cerebral cortex, but whereas in the iAD case, the area is virtually devoid of plaques with a persistence of Aβ in the cerebral vasculature. Scale bar = 1 mm.
