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(A) Fluorescence microscopic images of cellular internalization of non-targeted and targeted polymersomes in monolayer cultures of MCF7 cells in normoxia and hypoxia (scale bar: 50 μm). (B) Quantitative fluorescence integral density indicating cellular uptake after treating the MCF7 cells with targeted polymersomes in normoxia and hypoxia (n = 3, *p < 0.05, **p < 0.01).
