Table 3. Comparisons of clearance (mL/min/kg) and fractional excretion (%) of glucose, creatinine, major electrolytes between control, DM-cont, and DM-empa.

	Control (n = 3)	DM-cont (n = 3)	DM-empa (n = 5)
Cglu (× 102)	0.30±0.02	477.30±12.82*	1252.02±126.93*#
Ccre	9.61±0.22	13.46±0.72	13.32±1.54
Cca (× 102)	3.01±0.34	29.33±1.91*	16.18±4.51*#
Cna (× 102)	1.34±0.12	5.70±0.44*	3.67±0.39*#
Ck	0.45±0.05	2.58±0.54*	1.88±0.20*
Ccl (× 102)	2.74±0.22	9.78±0.35*	6.74±0.58*#
FEglu	0.03±0.002	35.62±1.71*	99.53±15.31*#
FEca	0.31±0.03	2.20±0.21*	1.27±0.34
FEna	0.14±0.01	0.43±0.05*	0.29±0.04*
FEk	4.66±0.45	19.05±3.85*	14.79±2.11*
FEcl	0.29±0.03	0.73±0.06*	0.53±0.06*

Clearance and fractional excretion of creatinine, sodium, and glucose after 12 weeks Data are represented as mean ± SE.

* p<0.05 vs control.

# p<0.05 vs DM-cont.