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. 2021 May 4;16(5):e0251135. doi: 10.1371/journal.pone.0251135

Table 5. Comparison of plasma amino acids concentration (nmol/mL) between control, DM-cont, and DM-empa after 12 week treatment period.

Control (n = 12) DM-cont (n = 16) DM-empa (n = 5)
proline 66.8±4.2 63.6±4.3 85.6±11.4
sarcosine 2.8±0.3 3.4±0.3 4.2±0.5*
glycine 107.3±8.6 107.6±7.7 162.0±16.8*#
glutamine 662.8±49.6 466.5±61.5* 400.7±37.8
ornithine 51.9±5.9 34.6±4.2* 31.4±4.2
tryptophan 47.3±2.9 37.8±3.5 31.0±2.9*
α-aminobutyric acid 7.6±1.1 5.7±0.3* 5.0±0.1*#
alanine 271.2±18.2 326.1±18.9 246.0±6.8
valine 96.7±6.4 134.9±10.5* 84.5±10.9#
isoleucine 34.9±2.2 46.1±3.7* 28.5±3.3#

Plasma concentration of amino acids showing VIP values ≥ 1. Data were represented as mean ± SE.

* p<0.05 vs control.

# p<0.05 vs DM-cont.