Table 3. Clinical symptoms before and after receiving the eradication therapy in Helicobacter pylori (HP) eradication failure group (n = 5).
| Before HP eradication | After HP eradication | p | |
|---|---|---|---|
| Total TWOQ-9 score | 4.8 ± 1.6 | 4.2 ± 2.2 | 0.529 |
| • Tremor | 0.8 ± 0.4 | 0.4 ± 0.5 | 0.178 |
| • Mood changes | 0.2 ± 0.4 | 0.4 ± 0.5 | 0.374 |
| Total GI symptom score | 10.8 ± 4.2 | 11.4 ± 1.3 | 0.763 |
| • Bloating | 1.8 ± 2.2 | 2.6 ± 2.1 | 0.338 |
| Total NMSQ score | 30.0 ± 14.9 | 25.2 ± 16.0 | 0.549 |
| PDQ-8 score | 8.6 ± 3.1 | 9.4 ± 6.4 | 0.759 |
| ‘Off’ UPDRS motor score | 33.0 ± 6.2 | 30.4 ± 8.2 | 0.610 |
| ‘On’ UPDRS motor score | 17.2 ± 7.6 | 12.0 ± 5.0 | 0.127 |
| Time up and go (sec) | 9.1 ± 2.6 | 8.3 ± 1.0 | 0.478 |
| L-Dopa onset time (min) | 23.7 ± 12.4 | 22.0 ± 6.7 | 0.645 |
| L-Dopa peak time (min) | 33.6 ± 12.8 | 28.9 ± 7.3 | 0.248 |
| Daily ‘on’ time (h) | 10.9 ± 2.3 | 9.3 ± 2.3 | 0.191 |
| Daily ‘off’ time (h) | 4.3 ± 2.3 | 4.9 ± 2.3 | 0.033 |
| Dyskinesia (h) | 1.6 ± 2.8 | 1.8 ± 3.3 | 0.374 |
TWOQ-9: Thai version of the 9-item Wearing-off Questionnaire; GI: Gastrointestinal; NMSQ: Non-Motor Symptoms Questionnaire; PDQ: Parkinson’s Disease Questionnaire; UPDRS: Unified Parkinson’s Disease Rating Scale; L-Dopa: Levodopa.
Statistically significant p-values are in bold.