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. 2021 May 4;16(5):e0251042. doi: 10.1371/journal.pone.0251042

Table 5. Demographic and clinical baseline status between Helicobacter pylori (HP) positive patients who succeeded and failed the eradication therapy.

Successful eradication (n = 17) Failure eradication (n = 5) P
Male gender, n (%) 7 (41.2) 5 (100.0) 0.020
Age (years) 61.1 ± 10.6 57.4 ± 9.8 0.495
Age at onset (years) 53.3 ± 10.3 50.4 ± 9.5 0.544
Smoking, n (%) 0 (0.0) 2 (40.0) 0.006
Vegetable/fruit (servings/day) 2.4 ± 0.6 1.4 ± 0.9 0.009
Disease duration (years) 7.6 ± 4.2 7.0 ± 5.5 0.834
SE-ADL 77.1 ± 4.7 80 ± 0.0 0.184
Hoehn & Yahr stage 2.2 ± 0.6 2.2 ± 0.3 0.976
‘Off’ UPDRS motor score 31.3 ± 10.9 33.0 ± 6.2 0.664
‘On’ UPDRS motor score 13.5 ± 7.5 17.2 ± 7.6 0.370
Total LED (mg/day) 774.3 ± 312.7 617.9 ± 156.9 0.152
    • Dopamine agonist, n (%) 14 (82.4) 5 (100.0) 0.312
    • COMT inhibitor, n (%) 9 (52.9) 1 (20.0) 0.193
    • MAO-B inhibitor, n (%) 1 (5.9) 1 (20.0) 0.334
    • Anticholinergic use, n (%) 6 (35.3) 1 (20.0) 0.519

SE-ADL: Schwab and England Activities of Daily Living Scale; UPDRS: Unified Parkinson’s Disease Rating Scale; LED: Levodopa equivalent dose; COMT: catechol-O-methyltransferase; MAO: Monoamine oxidase.

Statistically significant p-values are in bold.