Table 1.
LDTs and PBPs in M. tuberculosis (Mtb)
| name | RV # | enzyme type | MW (kDa) | |
|---|---|---|---|---|
| l,d-transpeptidases (LDTs) | LdtMt1 | RvO116c | LDT | 26.9 |
| LdtMt2 | Rv2518c | LDT | 43.4 | |
| LdtMt3 | Rvl433 | LDT | 28.7 | |
| LdtMt4 | RvO192 | LDT | 38.9 | |
| LdtMt5 | RvO483 | LDT | 47.9 | |
| penicillin-binding proteins (PBPs) | PonAl | Rv0050 | transglycosylase and DDT | 71.1 |
| PonA2 | Rv3682 | transglycosylase and DDT | 84.6 | |
| PBPA | Rv0016c | DDT | 51.6 | |
| PBPB | Rv2163c | DDT | 72.5 | |
| PBP-lipo | Rv2864 | DDT | 63.0 | |
| PBP4 | Rv3627c | carboxypeptidase | 46.8 | |
| DacB1 | Rv3330 | carboxypeptidase | 41.7 | |
| DacB2 | Rv2911 | carboxypeptidase | 29.7 | |
| BlaC | Rv2068c | β-lactamase | 32.6 | |
| Rv0907 | β-lactamase | 56.7 | ||
| Rvl367 | β-Mactamase | 41.3 |