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. 2021 May 4;36(3):785–793. doi: 10.1007/s10877-021-00709-w

Table 3.

Logistic regression models with and without random effects for the risk of ICU admission and/or in-hospital death

Fixed-effects model Mixed-effects model
Predictors Odds ratios CI p Odds ratios CI p
LUSs 1.28 1.08 – 1.65 0.016 5.64 1.19 – 26.68 0.029
Age 0.91 0.80 – 1.00 0.101 0.75 0.51 – 1.10 0.138
Random effects
σ2 3.29
τ00 4151.89 Subject
ICC 1.00
R2 Tjur 0.350 0.037/0.999
AIC 28.026 20,534

The most informative models according to AIC were those with LUSs and age as fixed effects terms; in the mixed effects model, addition of random between-subjects intercepts did improve the AIC but did not lead to improved model predictivity. The addition of other terms as specified in the Methods section did not significantly improve the AIC in either the fixed effects or mixed model. AIC Akaike’s information criterion, ICU intensive care unit