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. 2020 Nov 26;2(1):71–78. doi: 10.34067/KID.0000782020

Table 2.

Cox proportional hazard model for mortality, cardiovascular, stroke, and coronary events in American Indians from the Strong Heart Study (1989–1999)

Event Exposure: CKD Exposure: Loss >20 ml/min
Yr FU, Mean (SD) New Events Incidence Rate Hazard Ratio 95% Confidence Interval P value Hazard Ratio 95% Confidence Interval P value
Mortality 13.7 (6.4) 1198 0.0418 1.63 1.27 to 2.09 <0.001 3.37 2.70 to 4.19 <0.001
N=2098
All CVD 17.7 (4.5) 683 0.0196 1.16 0.84 to 1.59 0.37 1.43 1.09 to 1.88 0.01
N=1971
Stroke 19.0 (2.3) 174 0.0044 1.91 1.15 to 3.16 0.01 1.42 0.86 to 2.34 0.17
N=2081
CHF 18.7 (2.9) 256 0.0067 1.14 0.68 to 1.88 0.62 1.68 1.10 to 2.55 0.02
N=2035

Models excluding prevalent CVD, stroke, and/or CHF as relevant; adjusted for baseline eGFR and/or eGFR slope as relevant; all adjusted for age, sex, field center, smoking, alcohol use, BMI, education, income. FU, follow up; CVD, cardiovascular disease; BMI, body mass index.