Table 3.
Cancer-attributable Mortality Among People Living With Human Immunodeficiency Virus from 10 States, 2001–2015, by Population Subgroup
| Characteristic | Proportion of Deaths Preceded by Cancer, pd (95% CI) | Adjusted Hazard Ratio (95% CI) | Population-attributable Fraction (95% CI) | Crude Mortality Rate | Cancer-attributable Mortality Rate |
|---|---|---|---|---|---|
| Calendar period | |||||
| 2001–2005 | 15.1% (14.8%–15.5%) | 5.99 (5.82–6.17) | 12.6% (11.4%–13.8%) | 3839 | 484.0 |
| 2006–2010 | 18.0% (17.6%–18.3%) | 5.70 (5.55–5.85) | 14.8% (13.4%–16.2%) | 2582 | 382.3 |
| 2011–2015 | 20.7% (20.2%–21.3%) | 5.68 (5.49–5.88) | 17.1% (14.3%–19.9%) | 1835 | 313.6 |
| Sex | |||||
| Male | 18.5% (18.2%–18.8%) | 5.79 (5.68–5.91) | 15.3% (14.1%–16.4%) | 2628 | 401.4 |
| Female | 15.1% (14.7%–15.6%) | 5.76 (5.57–5.95) | 12.5% (10.9%–14.1%) | 2785 | 348.1 |
| Age category, years | |||||
| 20–39 | 13.3% (12.8%–13.8%) | 7.07 (6.77–7.39) | 11.4% (8.9%–13.9%) | 1671 | 191.1 |
| 39–59 | 17.1% (16.8%–17.4%) | 6.01 (5.89–6.14) | 14.2% (13.2%–15.3%) | 2855 | 406.5 |
| 60+ | 24.6% (23.9%–25.3%) | 4.42 (4.25–4.59) | 19.0% (16.9%–21.2%) | 4999 | 952.2 |
| Race/ethnicity | |||||
| Non-Hispanic white | 20.7% (20.1%–21.2%) | 5.74 (5.54–5.94) | 17.1% (14.7%–19.5%) | 2152 | 367.5 |
| Non-Hispanic black | 17.3% (17.0%–17.6%) | 5.78 (5.64–5.92) | 14.3% (13.1%–15.5%) | 3016 | 431.7 |
| Hispanic | 15.5% (15.0%–15.9%) | 5.93 (5.72–6.14) | 12.9% (11.1%–14.6%) | 2632 | 338.9 |
| Other | 17.7% (15.2%–20.2%) | 5.78 (4.85–6.90) | 14.6% (1.4%–27.9%) | 1540 | 225.6 |
| Risk group | |||||
| MSM | 22.5% (22.0%–23.1%) | 6.12 (5.93–6.32) | 18.9% (16.1%–21.6%) | 1683 | 317.3 |
| PWID | 14.1% (13.7%–14.5%) | 5.86 (5.68–6.06) | 11.7% (10.6%–12.8%) | 4602 | 537.5 |
| MSM + PWID | 14.9% (13.9%–15.9%) | 5.73 (5.31–6.20) | 12.3% (8.9%–15.7%) | 3132 | 385.6 |
| Heterosexual | 17.1% (16.5%–17.7%) | 5.97 (5.73–6.23) | 14.2% (11.9%–16.6%) | 2432 | 345.9 |
| Other/unknown | 18.3% (17.8%–18.8%) | 5.19 (5.01–5.38) | 14.8% (12.7%–16.8%) | 2750 | 406.4 |
| AIDS status | |||||
| AIDS | 18.2% (17.9%–18.4%) | 5.61 (5.51–5.71) | 14.9% (14.0%–15.8%) | 3556 | 530.8 |
| Human immunodeficiency virus only | 13.6% (13.1%–14.2%) | 9.04 (8.58–9.52) | 12.1% (8.6%–15.6%) | 1073 | 130.1 |
Mortality rates are per 100 000 person-years. Cox proportional hazards regression models use age as the time scale and are adjusted for sex, human immunodeficiency virus transmission risk group, race/ethnicity, time-dependent AIDS status, and attained calendar year.
Abbreviations: CI, confidence interval; MSM, men who have sex with men; PWID, people who inject drugs.