Table 6.
Correlation Between Methylation Detection Rate and the Clinicopathologic Features in Ade Stool Samples
| Clinicopathological Parameters | mSDC2 Rate (%) | p value | mTFPI2 Rate (%) | p value | Total Positive Detection Rate (%) | p value |
|---|---|---|---|---|---|---|
| Sex | ||||||
| Male (n=11) | 63.6 (7/11) | 1 | 63.6 (711) | 0.245 | 72.7 (8/11) | 0.509 |
| Female (n=5) | 80.0 (4/5) | 100.0 (5/5) | 100.0 (5/5) | |||
| Age | ||||||
| ≥ 60 (n=9) | 77.8 (7/9) | 0.596 | 66.7 (6/9) | 0.585 | 66.7 (7/9) | 1 |
| < 60 (n=7) | 57.1 (4/7) | 85.7 (6/7) | 85.7 (6/7) | |||
| Location | ||||||
| Left (n=13) | 76.9 (10/13) | 0.214 | 76.9 (10/13) | 1 | 84.6 (11/13) | 0.489 |
| Right (n=3) | 33.3 (1/3) | 66.7 (2/3) | 66.7 (2/3) | |||
| Size | ||||||
| ≥ 1 cm (n=8) | 87.5 (7/8) | 0.282 | 75.0(6/8) | 1 | 87.5 (7/8) | 1 |
| < 3 cm (n=8) | 50.0 (4/8) | 75.0 (6/8) | 75.0 (6/8) | |||
| Villous component | ||||||
| Yes (n=6) | 100.0 (6/6) | 0.093 | 83.3 (5/6) | 1 | 100.0 (6/6) | 0.25 |
| No (n=10) | 50.0 (5/10) | 70.0 (7/10) | 70.0 (7/10) | |||
| Dysplasia | ||||||
| Well differentiated (n=11) | 72.7 (8/11) | 1 | 72.7 (8/11) | 1 | 81.8 (9/11) | 1 |
| Poorly differentiated (n=5) | 60.0 (3/5) | 80.0 (4/5) | 80.0 (4/5) |
Notes: mSDC2 rate refers to detection rate of methylated SDC2; mTFPI2 rate refers to detection rate of methylated TFPI2; total positive rate refers to integrated detection rate of methylated SDC2 and TFPI2.