Table 2.
Top 50 proteins resolved in C. daubneyi extracellular vesicles following BLAST analysis of transcript identifiers.
| Transcript ID | Isoform | Unique peptides | Blast description | Organism | NCBI accession |
|---|---|---|---|---|---|
| TR26097|c0_g1 | i1 | 76 | ATPase family protein | Opisthorchis viverrini | OON14744.1 |
| TR18968|c0_g1 | i1 | 58 | Tubulin beta-3 | Fasciola hepatica | CAP72051.1 |
| TR17099|c2_g1 | i1 | 57 | Tubulin beta | Clonorchis sinensis | GAA51682.1 |
| TR21569|c0_g5 | i1 | 44 | No hit | No hit | No hit |
| TR9358|c0_g1 | i1 | 39 | Actin | Gossypium arboreum | XP_017626052.1 |
| TR19715|c0_g1 | i1 | 36 | Radixin | Carlito syrichta | XP_008054748.1 |
| TR21569|c0_g5 | i2 | 36 | No hit | No hit | No hit |
| TR17877|c2_g2 | i1 | 31 | Alpha-tubulin | Fasciola hepatica | CAO79602.1 |
| TR18958|c0_g1 | i1 | 28 | Alpha tubulin | Schistosoma japonicum | AAW27478.1 |
| TR19159|c0_g1 | i1 | 26 | Alpha tubulin | Clonorchis sinensis | GAA56421.1 |
| TR23254|c0_g1 | i1 | 24 | Leucyl aminopeptidase | Clonorchis sinensis | ABL11479.1 |
| TR24554|c0_g1 | i1 | 23 | alpha-glucosidase | Schistosoma mansoni | XP_018647945.1 |
| TR18070|c0_g1 | i1 | 22 | Acid sphingomyelinase phosphodiesterase | Clonorchis sinensis | GAA33847.2 |
| TR23757|c0_g1 | i1 | 22 | Alpha tubulin | Clonorchis sinensis | GAA38337.2 |
| TR24153|c0_g1 | i1 | 22 | Hypothetical protein | Opisthorchis viverrini | OON14506.1 |
| TR23969|c0_g1 | i1 | 21 | Tektin | Clonorchis sinensis | GAA33438.1 |
| TR23279|c0_g1 | i1 | 21 | Alpha tubulin | Fasciola hepatica | CAO79606.1 |
| TR18525|c0_g1 | i1 | 20 | 14-3-3 epsilon | Opisthorchis viverrini | OON22058.1 |
| TR21014|c0_g1 | i1 | 20 | SNaK1 | Schistosoma mansoni | AAL09322.1 |
| TR20466|c0_g1 | i1 | 19 | Calpain | Schistosoma mansoni | CCD74981.1 |
| TR20643|c0_g1 | i1 | 18 | annexin a7 | Schistosoma haematobium | KGB33756.1 |
| TR18939|c0_g1 | i1 | 18 | No hit | No hit | No hit |
| TR22034|c1_g4 | i3 | 18 | Aldolase | Opisthorchis viverrini | OON20700.1 |
| TR25036|c3_g1 | i13 | 17 | Cathepsin D | Fasciola gigantica | AEE69372.1 |
| TR25036|c3_g1 | i2 | 17 | Cathepsin D | Fasciola gigantica | AEE69372.1 |
| TR23288|c0_g1 | i1 | 16 | EF-hand domain | Schistosoma mansoni | CCD76447.1 |
| TR19073|c1_g2 | i1 | 16 | Hypothetical protein | Opisthorchis viverrini | OON16570.1 |
| TR18454|c0_g1 | i1 | 16 | Hypothetical protein | Opisthorchis viverrini | OON20759.1 |
| TR25036|c3_g1 | i1 | 16 | eukaryotic aspartyl protease | Opisthorchis viverrini | OON23093.1 |
| TR21569|c0_g5 | i7 | 16 | No hit | No hit | No hit |
| TR25036|c3_g1 | i14 | 14 | Cathepsin D | Clonorchis sinensis | GAA56870.1 |
| TR23782|c0_g2 | i1 | 14 | Leukotriene-A4 hydrolase | Clonorchis sinensis | GAA49617.1 |
| TR17046|c0_g1 | i1 | 15 | 14-3-3 epsilon | Clonorchis sinensis | AEO89649.1 |
| TR9216|c0_g1 | i1 | 15 | 14-3-3 protein | Opisthorchis viverrini | OON14987.1 |
| TR25395|c0_g2 | i2 | 15 | Hypothetical protein | Opisthorchis viverrini | XP_009165006.1 |
| TR17779|c0_g1 | i1 | 15 | Actin | Opisthorchis viverrini | XP_009173847.1 |
| TR25395|c0_g1 | i1 | 15 | Hypothetical protein | Opisthorchis viverrini | XP_009165006.1 |
| TR22003|c1_g5 | i1 | 14 | Tubulin beta | Cricetulus griseus | XP_007606483.1 |
| TR19892|c0_g1 | i1 | 14 | Hypothetical protein | Opisthorchis viverrini | OON16605.1 |
| TR18374|c0_g1 | i1 | 14 | Triose phosphate isomerase | Fasciola hepatica | AGJ83762.1 |
| TR25036|c3_g1 | i12 | 14 | Cathepsin E-A | Apaloderma vittatum | KFP91951.1 |
| TR17173|c0_g1 | i1 | 14 | leishmanolysin peptidase | Clonorchis sinensis | GAA54636.1 |
| TR17164|c0_g1 | i1 | 13 | glyceraldehyde 3- phosphate dehydrogenase | Clonorchis sinensis | GAA28380.1 |
| TR15297|c0_g1 | i1 | 13 | Chloride intracellular channel | Clonorchis sinensis | GAA38512.2 |
| TR19675|c0_g1 | i1 | 13 | JF-2 | Schistosoma japonicum | AAB49033.1 |
| TR25036|c3_g1 | i8 | 13 | Cathepsin D | Clonorchis sinensis | GAA56870.1 |
| TR23072|c0_g1 | i1 | 13 | EF-hand calcium-binding domain | Clonorchis sinensis | GAA51832.1 |
| TR24199|c0_g4 | i1 | 12 | Plastin-1 | Clonorchis sinensis | GAA29911.1 |
| TR21252|c0_g1 | i1 | 12 | 33kDa inner dynein arm light chain | Schistosoma japonicum | CAX73643.1 |
| TR25837|c0_g3 | i3 | 12 | EF-hand domain-containing family member | Clonorchis sinensis | GAA35263.2 |
Proteins were ranked based on the number of unique peptides sequenced during tandem LC-MSMS and BLAST identifiers chosen based on E-values.