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. 2021 May 5;13:8. doi: 10.1186/s41479-021-00088-5

Table 5.

Association between isolation of Streptococcus pneumoniae with respiratory viruses, and, between the density (Log copies/ml) of Streptococcus pneumoniae with viruses in the nasopharynx of children

Pneumococcal colonization Pneumococcal density
na ORb 95% CIc P n Coeffd 95% CI P
Overall children
 Virus presence 83 3.93 1.47–10.5 0.006 31 3.603 .44–6.7 0.027
 1 virus 83 3.85 1.15–12.8 0.028 31 0.533 −3.2-4.3 0.77
  > 1 virus 83 2.25 0.62–8.1 0.21 31 5.06 1.1–9 0.01
 Rhinovirus 83 3.13 0.99–9.9 0.052 31 4.52 1.1–7.9 0.01
 Adenovirus 83 6 1.12–32 0.036 31 1.62 −2.7-6 0.45
Children living with HIV
 Rhinovirus 43 15.6 1.66–146 0.016 16 4.22 −0.2-8.6 0.06
 Rhinovirus + S. aureus 43 8.7 1.42–54 0.019
 Adenovirus 43 4.16 0.66–26 0.12 16 −0.46 −6.1, 5.1 0.86
HIV uninfected children
 Rhinovirus 40 1 .20–4.9 1 15 2.7 −1.9-7.3 0.23
 Adenovirus 40 NAe NA NA 15 2.77 −2.7, 8.3 0.3

an number of observations; bOR Odds ratio; cCI Confidence interval; dRegression coefficient; eNA Not available