Table 2.
Sensitivity Analysis Demonstrating the Effect of Decay Rate on the Number of Infections Defined Using Paired Serology Among Participants in a Longitudinal Cohort Study Conducted in Pau da Lima, Brazil, 2013–2015
| Titer Decay Rate | Total Infections a Per 6-Month Period, Median (IQR) | |||
|---|---|---|---|---|
| Period 1 | Period 2 | Period 3 | Period 4 | |
| Conventional (no decay) | 64 | 96 | 47 | 66 |
| 0.981 (R/4) | 66 (65–67) | 98 (97–99) | 51 (50–53) | 69 (68–71) |
| 0.962 (R/2) | 69 (68–70) | 100 (99–101) | 56 (55–58) | 73 (72–75) |
| 0.926 (R) | 73 (72–74) | 106 (105–108) | 64 (63–65) | 87 (85–88) |
| 0.857 (2R) | 82 (81–83) | 120 (120–121) | 77 (76–78) | 101 (100–101) |
Abbreviations: IQR, interquartile range; R, estimated decay rate.
a Total infections consists of seroconversions plus 4-fold rises.