Table 2.
Patients' demographics, liver disease characteristics, and clinical presentation (means ± standard deviation).
| FHVP7 decreased or unchanged (N = 40) | FHVP increased (N = 22) | p value | Responders (N = 46) | Nonresponders (N = 16) | p value | |
|---|---|---|---|---|---|---|
| Mean age (years) | 55.50 ± 10.61 | 52.77 ± 12.58 | 0.369 | 54.00 ± 11.44 | 56.06 ± 11.22 | 0.535 |
| Gender male/female | 19/21 | 15/7 | 0.182 | 27/19 | 7/9 | 0.386 |
| Etiology virus/alcoholic/PBC1/others | 21/5/3/11 | 16/2/2/2 | 0.326 | 30/5/3/8 | 7/2/2/5 | 0.465 |
| PLT2 (×109/L) | 67.40 ± 40.09 | 78.82 ± 68.46 | 0.410 | 74.43 ± 58.17 | 62.88 ± 24.65 | 0.446 |
| TBil3 (μmol/L) | 16.40 ± 8.38 | 22.63 ± 15.39 | 0.089 | 19.16 ± 10.65 | 17.02 ± 14.40 | 0.531 |
| Creatinine (μmol/L) | 60.55 ± 19.56 | 62.23 ± 16.48 | 0.734 | 60.84 ± 19.65 | 62.03 ± 14.75 | 0.825 |
| Albumin (g/L) | 34.74 ± 4.03 | 36.71 ± 4.89 | 0.094 | 35.18 ± 4.69 | 36.16 ± 3.56 | 0.450 |
| PT4 (s) | 14.51 ± 2.67 | 14.17 ± 1.75 | 0.603 | 14.80 ± 2.52 | 13.19 ± 1.39 | 0.018 |
| INR5 | 1.25 ± 0.22 | 1.23 ± 0.15 | 0.661 | 1.28 ± 0.20 | 1.14 ± 0.12 | 0.021 |
| CTP6 scores | 7 (5-9) | 6.5 (5-8) | 0.799 | 7 (5-9) | 6 (5-8) | 0.117 |
| CTP stage A/B/C | 20/20/0 | 11/11/0 | 1.000 | 20/26/0 | 11/5/0 | 0.146 |
| Ascites8 | ||||||
| No/mild/moderate/massive | 15/12/12/1 | 9/10/3/0 | 0.374 | 16/17/12/1 | 8/5/3/0 | 0.698 |
| Splenectomy yes/no | 1/39 | 2/20 | 0.285 | 3/43 | 0/16 | 0.562 |
| Median follow-up time (m) | 11.50 | 13.00 | 0.740 | 13.00 | 10.50 | 0.331 |
1PBC: primary biliary cirrhosis; 2PLT: platelets; 3TBil: total bilirubin; 4PT: prothrombin time; 5INR: international standard ratio; 6CTP: Child-Turcotte-Pugh; 7FHVP: free hepatic vein pressure; 8ascites: (1) mild: patients generally have abdominal distension, the ascites can only be detectable by an ultrasound examination, and the depth is <3 cm. (2) Moderate: the patient often has moderate and symmetrical abdominal distension, and the depth is 3–10 cm. (3) Massive: the patient has a significant bloating. The ascites detected by ultrasound occupy the entire abdominal cavity, and the depth is >10 cm.