Table 2:

Association between time to colonoscopy and risk of incident and fatal CRC among Veterans with an abnormal FIT/FOBT, represented as hazard ratios and 95% confidence intervals; 1999–2015 (n=204,733).

Variable	No. of Patients	No. cases due to CRC	No. fatal CRC cases	Incident CRC Unadjusted HR (95% CI)	Incident CRC Adjusted HR (95% CI)	Fatal CRC Unadjusted HR (95% CI)	Fatal CRC Adjusted HR (95% CI)
Time to Colonoscopy after abnormal FIT/FOBT
1–3 months	61,613	2050	454	REF	REF	REF	REF
4–6 months	39,948	1312	335	0.93 (0.87–1.00)	0.91 (0.85–0.97)	1.00 (0.87–1.15)	0.95 (0.83–1.10)
7–9 months	18,217	605	168	0.92 (0.84–1.01)	0.89 (0.81–0.98)	1.05 (0.88–1.26)	1.00 (0.84–1.19)
10–12 months	10,187	354	89	0.96 (0.86–1.08)	0.93 (0.83–1.05)	0.99 (0.79–1.24)	0.94 (0.74–1.17)
13–15 months	7,388	308	63	1.17 (1.03–1.31)	1.13 (1.00–1.27)	0.98 (0.75–1.27)	0.93 (0.72–1.21)
16–18 months	5,478	253	65	1.29 (1.13–1.47)	1.25 (1.10–1.43)	1.36 (1.05–1.77)	1.27 (0.98–1.65)
19–21 months	4,283	200	58	1.31 (1.13–1.51)	1.28 (1.11–1.48)	1.57 (1.19–2.06)	1.52 (1.15–1.99)
22–24 months	3,595	166	46	1.28 (1.09–1.50)	1.26 (1.07–1.47)	1.44 (1.06–1.95)	1.39 (1.03–1.88)
> 24 months	54,024	1658	431	0.81 (0.76–0.86)	0.86 (0.80–0.92)	0.82 (0.72–0.93)	0.89 (0.78–1.02)

HR: Hazard Ratio; CI: Confidence Interval; No.: Number

Adjusted for age, sex, race/ethnicity, smoking, Charlson Comorbidity Index, and BMI