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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Curr Opin Struct Biol. 2021 Jan 22;67:195–204. doi: 10.1016/j.sbi.2020.12.004

Figure 2: Structural comparison of A3A-ssDNA and A3B-ssDNA.

Figure 2:

The structural comparison of A3A-ssDNA (PDB: 5KEG) (a) and A3B-ssDNA model (c). Proteins are shown as cartoon representation (iceblue for A3A while green for A3B). ssDNAs are shown as orange sticks. Gatekeeper residues are shown as salmon sticks with critical intermolecular interactions shown as gray dashes. The intermolecular interactions of gatekeeper residue for coordinating DNA binding (b) H29 in A3A and(d) R211 in A3B. The different loop-1 residues in A3Bctd-QMΔloop3-A3Aloop1 structure (PDB: 5TD5; yellow sticks, cyan cartoon) and wild type A3B-ssDNA model are shown in (e).