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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Heart Rhythm. 2021 Jan 26;18(5):709–716. doi: 10.1016/j.hrthm.2021.01.021

Table 2.

Association between AF burden and outcomes among patients with and without heart failure at baseline.

Unadjusted Model Adjusted Model
Hazard Ratio (95% CI) P-value Hazard Ratio (95% CI) P-value
Patients with no heart failure at baseline

New Onset HF at 1 Year
 Percent in AF, per 10 1.076(1.050, 1.101) <.001 1.089 (1.063, 1.115) <.001
 Maximum Duration, per 1 hr 1.002(1.000, 1.003) 0.012 1.002(1.000, 1.002) 0.005
Mortality at 1 Year
 Percent in AF, per 10 1.035 (0.994, 1.077) 0.100 1.053(1.011, 1.096) 0.012
 Maximum Duration, per 1 hr 0.998(0.993, 1.003) 0.461 0.999(0.995, 1.003) 0.326

Patients with heart failure at baseline

HF Hospitalization at 1 Year
 Percent in AF, per 10 1.044(1.034, 1.054) <.001 1.048(1.038, 1.059) <.001
 Maximum Duration, per 1 hr 1.001(1.000, 1.001) <.001 1.001(1.000, 1.001) 0.004
Mortality at 1 Year
 Percent in AF, per 10 1.064(1.047, 1.081) <.001 1.063(1.046, 1.080) <.001
 Maximum Duration, per 1 hr 1.001(1.000, 1.001) 0.024 1.001(1.000, 1.001) 0.005

AF: atrial fibrillation; HF: heart failure; CI: confidence interval.